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With the Guava® Muse® cell analyzer, you can achieve highly quantitative results at a fraction of the price, effort, and time. The Muse cell analyzer packs 3-parameter analysis into a compact, easy to use benchtop device, making flow cytometry accessible to anyone, anytime. A user-friendly touchscreen interface, intuitive cell analysis software, and optimized assays work to simplify your research.


Laser-Based Fluorescence Detection

The system delivers high-performance cell analysis using a microcapillary technology and miniaturized optics which occupy one-tenth the space of a typical cytometer. Laser-based fluorescence detection of each cell event can evaluate up to 3 cellular parameters. As a result, the Muse system provides more quantitative results than non-flow based imaging systems, which only examine up to two parameters, are time-consuming, and provide less quantitative data.

Customer Testimonials

As scientists, peer review is the gold standard by which we assess technologies, second only to trying out tools and reagents ourselves. Routine but essential cell analysis assays are faster, easier, and more data-rich with the Muse instrument. Get more insight on the Muse cell analyzer from our customers.
  • "My lab has been using the Muse for about one year now and I can say that the Muse is exceptional. The Muse cuts the time of manually counting by half... I would recommend the Muse to anyone who does manual counting."
    • T. Weaver, Duke University, USA
  • "I just started to use Muse cell analyzer and I'm happy with it at least for now. The machine is user-friendly, easy to learn and maintain. The thing I have to mention is I had a good experience with the customer service. Larry is very helpful."
    • M. Zhao, University at Buffalo, USA
  • "We bought the Muse in order to do quick experiments without having the full set up of a FACS... We are able to do quick and accurate cell counts, then run assays in all the convenience of the lab. The results seem to be consistent with what we would be getting using the FACS."
    • M. de la Vega, University of Hawaii, USA
Accurate Cell Concentrations

The Muse cell analyzer counts cells more accurately than manual hemocytometry or image-based automated analysis.​

Muse cell analysis data was correlated with the theoretical concentration with slope closest to 1, indicating superior accuracy.

Precise Results

The Muse cell analyzer counts cells and measures viability more precisely with smaller coefficients of variation (%CV) than manual hemocytometry or image-based automated analysis. Higher %CVs were observed for the Trypan blue-based methods, particularly at lower cell concentrations.

Analysis Cell Concentration Visibility
Average % CV % CV Range Average % CV % CV Range
Image-based Automated Counter 9.2% 1.2-23.3% 3.7% 0.8-12.1%
Manual Hemocytometer 9.2% 6.3% 4.5% 0.5-9.2%
Muse Cell Analyzer 4.0% 0.3-8.8% 2.2% 0.4-5.6%
Comprehensive Cell Health Measurements

Evaluation of cell health and the potential mechanism of action, is critical is various aspects of drug discovery and cell biology.

Muse® Cell Analyzer: Kits & Reagents

For the assays you rely on most, we’ve developed optimized kits, validated for robust performance on the Muse® cell analyzer. Typical cell preparation protocols have been condensed and simplified, so sample preparation is fast and easy. You don’t need to optimize any software settings — the Muse instrument calculates all gating parameters and thresholds for you. Spend less time with experimental setup, avoid reagent waste, and save money.

What method do you currently use for fundamental cell counting, cell health, and signaling assays?

Other Cell Analysis Techniques Muse® Assays
  • Hemacytometer:
    • Limited due to low-resolution dye uptake for viability determination
    • Subject to manual counting and calculation errors
  • Muse® Count and Viability Assay
    • Precise, fluorescence-based live/dead cell discrimination
    • Microcapillary fluidics for direct cell counts with industry-leading accuracy
  • Brightfield Microscopy-Based Automated Hemocytometer/Cell Analyzer:
    • Low accuracy based on small number of cells analyzed, and limited to count and viability measurement
  • Muse® Assays
    • Fluorescent reagents generate signal based on specificity for unique targets
    • Statistical significance achievable from rapid acquisition of thousands of cells
  • Western Blot and Other Bulk Assays:
    • Population heterogeneity is lost when cells are pooled
    • Methods are time-consuming and require expertise
    • Reagents must be validated and optimized
    • Data is qualitative or semi-quantitative at best
  • Muse® Assays
    • Single-cell data is obtained from every sample
    • Extremely simple ‘pipette only’ assays
    • Validated and optimized for multiple cell types
  • Large, Open-System Flow Cytometer:
    • Reagents must be validated for application
    • Optimization is time-consuming and uses precious sample
    • Software settings must be determined independently
  • Muse® Assays
    • Fluorescent reagents are chosen for compatibility with lasers and detectors and optimized on multiple cell types
    • Assays have validated, optimized sample preparation protocols and pre-set software settings
Kits and Assays
Product Category Part Number
Guava® SARS-CoV-2 Multi-Antigen Antibody Kit Protein Detection FCPA100101​
Muse® Count & Viability Kit 40 mL Cell Health MCH100102
Muse® Count & Viability Kit 240 mL Cell Health MCH600103
Muse® Count & Viability Kit (200X) Cell Health MCH100104
Muse® Annexin V & Dead Cell Kit Cell Health MCH100105
Muse® Cell Cycle Kit Cell Health MCH100106
Muse® Cell Dispersal Reagent Cell Health MCH100107
Muse® Caspase-3/7 Kit Cell Pathways MCH100108
Muse® MultiCaspase Kit Cell Pathways MCH100109
Muse® Autophagy LC3-Antibody Based Kit Cell Pathways, Autophagy MCH200109
Muse® Mitopotential Kit Cell Health MCH100110
Muse® Oxidative Stress Kit Cell Health MCH100111
Muse® Nitric Oxide Kit Cell Health MCH100112
Muse® Ki67 Proliferation Kit Cell Health MCH100114
Muse® Human CD4 T Cell Kit Immunology MIM100101
Muse® Human CD8 T Cell Kit Immunology MIM100102
Muse® Human B Cell Kit Immunology MIM100103
Muse® H2A.X Activation Dual Detection Kit Cell Pathways MCH200101
Muse® EGFR-RTK Activation Dual Detection Kit Cell Pathways MCH200102
Muse® PI3K Activation Dual Detection Assay Kit Cell Pathways MCH200103
Muse® MAPK Activation Dual Detection Assay Kit Cell Pathways MCH200104
Muse® Bcl-2 Activation Dual Detection Assay Kit Cell Pathways MCH200105
Muse® Multi-Color DNA Damage Kit Cell Pathways MCH200107
Muse® PI3K/MAPK Dual Pathway Activation Kit Cell Pathways MCH200108
Muse® Malaria P.f-P.v. Detection Kit Malaria Research MPA100101

For Research Use Only. Not for use in diagnostic or therapeutic procedures.