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Why is Immuno-Oncology Important?

Scientists devoted to immuno-oncology (IO) are establishing new ways to target and destroy cancer cells through personalized immunotherapies. Thanks to decades of research and advances in technologies, scientists and healthcare professionals have richly documented the human adaptive and innate immune response mechanisms and are now using that information to design and administer personalized immunotherapies.

These therapies may inhibit or enhance different aspects of the immune response, depending on the action needed to hinder and destroy the life-threatening cancer cells within the human host.

Cytek Solutions Enable the World’s Most Cutting Edge Immuno-Oncology Research.

Explore the case study below to see how.
Case Study

Cancer Vaccine Research at Amsterdam University Medical Center

At the Amsterdam University Medical Center, researchers are using liposomes to target antigen-presenting cells critical for cancer vaccine efficacy. Cancer vaccines help cancer patients positively respond to checkpoint inhibitors by re-invigorating the immune system’s T cell response.

Cancer vaccine effectiveness can be suboptimal, so this group is looking to augment vaccine potency by specifically targeting cells of interest with liposomes. Subsequent studies on both dosing and route of vaccine administration pave the way for more effective cancer vaccines. See how the Cytek Aurora helped this team throughout their research by reading their publication.

Creating New Cancer Vaccine Delivery Vehicles

Quantification of antigen-presenting cells and T cells by the Cytek Aurora in steps 2, 3, and 5 in this research group’s experimental workflow helps the team develop and optimize their cancer vaccine delivery protocol.

Full Spectrum Flow Cytometry: Powerful Technology for Cancer Immunotherapy Research

Read this Review Article in Frontiers in Molecular Biosciences to learn more.
Case Study

Cancer Vaccine Research at Amsterdam University Medical Center

At the Agency for Science, Technology, and Research in Singapore, researchers like John Connolly develop patient-specific modified dendritic cells with altered immune cell targeting activity and counteract the effect of cancer cells in the immune system. Once the cells have been collected from the patient and modified, they are cultured to generate more of them and re-injected into the patient. Blood samples are collected from the patient at specific time intervals post-injection to monitor and evaluate if the cancer cells are being eliminated successfully.

The Cytek Aurora enables this team to characterize and evaluate the blood samples and the different cells it contains. Learn more about the Cytek Aurora’s flexible software and multiplexing capabilities that make it an integral part in monitoring the effects of personalized cell therapy.

Personalized Cell Therapy