TDS | SDS

The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.

The 30-F11 antibody is widely used as a leukocyte marker for B cells, T cell subsets and NK cell subsets.

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Name	violetFluor™ 450 Anti-Mouse CD45 (30-F11)
Cat. No.	75-0451
Alternative Names	Leukocyte Common Antigen, LCA, Ly-5
Gene ID	19264
Clone	30-F11
Isotype	Rat IgG2b, κ
Reactivity	Mouse
Format	violetFluor™ 450
Application	Flow Cytometry

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