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SJL splenocytes were stained with 0.5 ug violetFluor™ 500 Anti-Mouse CD45.1 (85-0453) (solid line) or 0.5 ug violetFluor™ 500 Mouse IgG2a isotype control (dashed line).

violetFluor™ 500 Anti-Mouse CD45.1 (A20)

SKU 85-0453-U025
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The A20 antibody reacts with mouse CD45.1, also known as Ly5.1, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.

The A20 antibody is typically used as a leukocyte marker in Ly5.1 mouse strains: SJL/J, DA, STS/A and RIII. The antibody has been demonstrated to specific for CD45.1 and is not cross-reactive with CD45.2 bearing cells.

Recent Publications:
Lin CC, Bradstreet TR, Schwarzkopf EA, Jarjour NN, Chou C, Archambault AS, Sim J, Zinselmeyer BH, Carrero JA, Wu GF, Taneja R, Artyomov MN, Russell JH and Edelson BT. 2016. J Exp Med. 213(2): 251-271. (Flow Cytometry)

Name violetFluor™ 500 Anti-Mouse CD45.1 (A20)
Cat. No. 85-0453
Alternative Names SJL, Ly5.1
Gene ID 19264
Clone A20
Isotype Mouse IgG2a, κ
Reactivity Mouse
Format violetFluor™ 500
Application Flow Cytometry
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