Purified Anti-Mouse MHC Class II (I-A/I-E) (M5/114.15.2)
The M5/114.15.2 antibody reacts with mouse MHC Class II alloantigens I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek, as well as being cross-reactive with mouse cells of H-2p and H-2r haplotype. MHC Class II is widely expressed by mouse immune cells bearing these alloantigens, including T and B cells, monocytes, macrophages, and dendritic cells. The antibody does not react with the following alloantigens: I-Af, I-Ak, I-As, or NOD H-2g7
The M5/114.15.2 antibody may be used for analysis of mouse cells expressing MHC Class II alloantigens as described. Please note that the M5/114.15.2 clone may also be referred to as M5/114 in the literature.
Zhang Y, Wang Y, Zheng G, Liu Y, Li J, Huang H, Xu C, Zeng Y, Zhang X, Qin J, Dai C, Hambrock HO, Hartmann U, Feng B, Mak KK, Liu Y, Lan HY, Huang Y, Zheng ZH, Xia Y. Follistatin-like 1 (FSTL1) interacts with Wnt ligands and Frizzled receptors to enhance Wnt/β-catenin signaling in obstructed kidneys in vivo. J Biol Chem. 2022 May 4:102010. doi: 10.1016/j.jbc.2022.102010. Epub ahead of print. PMID: 35525270
|Name||Purified Anti-Mouse MHC Class II (I-A/I-E) (M5/114.15.2)|
|Alternative Names||MHC II, IA, IE, I-A/E, IA/IE|
|Isotype||Rat IgG2b, κ|
|Application||Flow Cytometry, IF, IHCF, IP, Western Blot, Electron Microscopy|