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Purified Anti-Mouse MHC Class II (I-A/I-E) (M5/114.15.2)

Purified Anti-Mouse MHC Class II (I-A/I-E) (M5/114.15.2)

SKU 70-5321-U100
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The M5/114.15.2 antibody reacts with mouse MHC Class II alloantigens I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek, as well as being cross-reactive with mouse cells of H-2p and H-2r haplotype. MHC Class II is widely expressed by mouse immune cells bearing these alloantigens, including T and B cells, monocytes, macrophages, and dendritic cells. The antibody does not react with the following alloantigens: I-Af, I-Ak, I-As, or NOD H-2g7

The M5/114.15.2 antibody may be used for analysis of mouse cells expressing MHC Class II alloantigens as described. Please note that the M5/114.15.2 clone may also be referred to as M5/114 in the literature.


Recent Citations:

Zhang Y, Wang Y, Zheng G, Liu Y, Li J, Huang H, Xu C, Zeng Y, Zhang X, Qin J, Dai C, Hambrock HO, Hartmann U, Feng B, Mak KK, Liu Y, Lan HY, Huang Y, Zheng ZH, Xia Y. Follistatin-like 1 (FSTL1) interacts with Wnt ligands and Frizzled receptors to enhance Wnt/β-catenin signaling in obstructed kidneys in vivo. J Biol Chem. 2022 May 4:102010. doi: 10.1016/j.jbc.2022.102010. Epub ahead of print. PMID: 35525270

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Name Purified Anti-Mouse MHC Class II (I-A/I-E) (M5/114.15.2)
Cat. No. 70-5321
Alternative Names MHC II, IA, IE, I-A/E, IA/IE
Gene ID 14961/14969
Clone M5/114.15.2
Isotype Rat IgG2b, κ
Reactivity Mouse
Format Purified
Application Flow Cytometry, IF, IHCF, IP, Western Blot, Electron Microscopy
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