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Purified Anti-Mouse CD49b (HMa2)
SKU 70-0491-U100
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Description
The HMa2 antibody reacts with mouse CD49b, a 150 kDa glycoprotein member of the integrin αfamily. CD49b, also known as integrin αalpha2, associates non-covalently with CD29 (integrin αbeta1) to form the VLA-2 heterodimer. VLA-2 integrin αs function as cellular receptors for collagen and laminin. CD49b is expressed by platelets, intestinal epithelial cells, NK cells, epithelial cells, and a subset of CD4+ T cells. CD49b plays an essential role in mediating the adhesion of cells to the extracellular matrix.
| Name | Purified Anti-Mouse CD49b (HMa2) |
|---|---|
| Cat. No. | 70-0491 |
| Alternative Names | α2 integrin α, VLA-2 α chain, integrin α?2 chain, ITGA2, HM?2 |
| Gene ID | 16398 |
| Clone | HMa2 |
| Isotype | Armenian Hamster IgG |
| Reactivity | Mouse |
| Format | Purified |
| Application | Flow Cytometry, Functional Assays |