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Purified Anti-Mouse CD279 (PD-1) (RMP1-14)

Purified Anti-Mouse CD279 (PD-1) (RMP1-14)

SKU 70-9982-U100
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The RMP1-14 antibody is specific for mouse CD279, also known as programmed death-1 (PD-1), a 55 kDa glycoprotein member of the Ig superfamily of molecules. PD-1 exists in a monomeric form that is expressed by CD4- CD8- thymocytes, where it participates in the processes of clonal selection, elimination of autoreactive lymphocytes, and development of tolerance. PD-1 expression is also inducible upon activation of mature T cells, where it has been proposed to interact with the co-stimulatory receptor CD80 to limit T cell activation. Two ligands for PD-1, known as PD-L1 (B7-H1) and PD-L2 (B7-DC) are differentially expressed on T and B cells, monocytes, macrophages, NK cells or dendritic cells.
Name Purified Anti-Mouse CD279 (PD-1) (RMP1-14)
Cat. No. 70-9982
Gene ID 18566
Clone RMP1-14
Isotype Rat IgG2a, κ
Reactivity Mouse
Format Purified
Application Flow Cytometry, Functional Assays
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