Shopping Cart
Purified Anti-Human CD3 (Hit3a)

Purified Anti-Human CD3 (Hit3a)

SKU 70-0039-U100
Regular price


task_alt Added to cart.
View Cart or Continue shopping.

The Hit3a antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor - CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

The Hit3a antibody is a widely used phenotypic marker for human T cells. In addition, binding/cross-linking of Hit3a antibody to CD3e can induce cell activation. 

Name Purified Anti-Human CD3 (Hit3a)
SKU 70-0039
Data Sheets TDS | SDS
Alternative Names Leu-4, T3
Gene ID 916
Clone Hit3a
Isotype Mouse IgG2a, κ
Reactivity Human
Cross Reactivity Chimpanzee
Format Purified
Application Flow Cytometry, Functional Assays, IHCF, IP

For Research Use Only. Not intended for use in diagnostic procedures.


Price calculated at checkout.