The mouse monoclonal antibody 1A5 recognizes an extracellular epitope of CD170 (Siglec-5, sialic acid binding Ig-like lectin 5), a transmembrane glycoprotein expressed strongly by neutrophils, macrophages activated during infections, monocytes, and dendritic cells. As in case with other anti-CD170 antibodies, this antibody crossreacts with Siglec-14, whose first two Ig domains are almost identical to those of CD170.

PRODUCT DETAILS

Clone: 1A5

Specificity: CD170 (Siglec-F)

Reactivity: Human, Non-Human Primate

Format: Purified

Isotype: Mouse IgG1

Application: FC, IP, ICC, ELISA

Storage: 2-8°C protected from light.Do not freeze

Formulation: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Flow cytometry: Recommended dilution: 1-4 μg/ml.
Immunohistochemistry: Recommended dilution: 5-10 μg/ml.

REFERENCES

1. Angata T, et al. 2006. FASEB J 20:1964-73.
2. Schuster P, et al. 2010. Immunology 129:234-47.

For research use only. Not intended for use in diagnostic procedures.