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C57Bl/6 bone marrow cells were stained with APC Anti-Mouse CD11b (20-0112) and 0.125 ug PerCP-Cy5.5 Anti-Mouse F4/80 Antigen (65-4801) (right panel) or 0.125 ug PerCP-Cy5.5 Rat IgG2b isotype control (left panel).

PerCP-Cyanine5.5 Anti-Mouse F4/80 Antigen (BM8.1)

SKU 65-4801-U025
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The BM8.1 antibody is specific for mouse F4/80 antigen, a 125 kDa transmembrane protein widely expressed by members of the mononuclear phagocyte system and considered to be a key marker for mature macrophage cells. F4/80 is differentially expressed during myeloid cell development, and may be regulated by certain cytokines within the tissue microenvironment. Other cell types shown to express this antigen include Langerhans cells, Kupffer cells and dendritic cell subsets. BM8.1 is widely used together with antibodies to CD115 (c-fms), CD11b and CD11c to identify myeloid / macrophage cells by flow cytometry.

Recent Publications:
Skeldon AM, Morizot A, Douglas T, Santoro N, Kursawe R, Kozlitina J, Caprio S, Mehal WZ and Saleh M. 2015. J Immunol. doi: 10.4049/jimmunol.1501529. (Flow Cytometry)

Peña CG, Nakada Y, Saatcioglu HD, Aloisio GM, Cuevas I, et al. 2015. J Clin Invest. doi: 10.1172/JCI82152. (Flow Cytometry)
Name PerCP-Cyanine5.5 Anti-Mouse F4/80 Antigen (BM8.1)
Cat. No. 65-4801
Alternative Names EMR1, Ly71
Gene ID 13733
Clone BM8.1
Isotype Rat IgG2b, κ
Reactivity Mouse
Format PerCP-Cyanine5.5
Application Flow Cytometry
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