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PerCP-Cyanine5.5 Anti-Mouse CD49d (R1-2)
SKU 65-0492-U025
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Description
The R1-2 monoclonal antibody reacts with mouse CD49d, a 150kD glycoprotein member of the integrin αfamily. CD49d is also known as integrin αalpha4 (ITGA4). Together with integrin αbeta1 (CD29), CD49d forms the VLA-4 heterodimer that serves as a receptor for fibronectin and VCAM-1. VLA-4 is widely expressed on lymphocytes, monocytes, thymocytes, and NK cells. CD49d can dimerize with integrin αbeta7 to form a receptor that binds the mucosal vascular addressin molecule, MAdCAM-1.
| Name | PerCP-Cyanine5.5 Anti-Mouse CD49d (R1-2) |
|---|---|
| Cat. No. | 65-0492 |
| Alternative Names | ?4 integrin α, VLA-4 ? chain, integrin α?4, ITGA4 |
| Gene ID | 16401 |
| Clone | R1-2 |
| Isotype | Rat IgG2b, κ |
| Reactivity | Mouse |
| Format | PerCP-Cyanine5.5 |
| Application | Flow Cytometry |