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C57Bl/6 splenocytes were stained with 0.25 ug PerCP-Cyanine5.5 Anti-Mouse CD49d (65-0492) (solid line) or 0.5 ug PerCP-Cyanine5.5 Rat IgG2b isotype control (dashed line).

PerCP-Cyanine5.5 Anti-Mouse CD49d (R1-2)

SKU 65-0492-U025
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The R1-2 monoclonal antibody reacts with mouse CD49d, a 150kD glycoprotein member of the integrin αfamily. CD49d is also known as integrin αalpha4 (ITGA4). Together with integrin αbeta1 (CD29), CD49d forms the VLA-4 heterodimer that serves as a receptor for fibronectin and VCAM-1. VLA-4 is widely expressed on lymphocytes, monocytes, thymocytes, and NK cells. CD49d can dimerize with integrin αbeta7 to form a receptor that binds the mucosal vascular addressin molecule, MAdCAM-1.

Name PerCP-Cyanine5.5 Anti-Mouse CD49d (R1-2)
Cat. No. 65-0492
Alternative Names ?4 integrin α, VLA-4 ? chain, integrin α?4, ITGA4
Gene ID 16401
Clone R1-2
Isotype Rat IgG2b, κ
Reactivity Mouse
Format PerCP-Cyanine5.5
Application Flow Cytometry
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