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C57Bl/6 splenocytes were stimulated with anti-IgM and anti-CD40 for 4 days. Cells were then stained with 0.5 ug PerCP-Cyanine5.5 Anti-Mouse CD252 (65-5905) (solid line) or 0.5 ug PerCP-Cyanine5.5 Rat IgG2b isotype control (dashed line).

PerCP-Cyanine5.5 Anti-Mouse CD252 (OX40 Ligand) (RM134L)

SKU 65-5905-U025
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The RM134L antibody recognizes CD252, also known as OX-40 Ligand or CD134 Ligand, a member of the TNF-α superfamily that is present on the surface of antigen presenting cells and activated B lymphocytes. The OX-40 Ligand interacts with OX-40 (CD134) which is expressed primarily on activated T cells. This costimulatory interaction leads to increased proliferation and IL-2 production responses of activated T cells, and at the same time enhances proliferation and immunoglobulin secretion by activated B cells.

The RM134L antibody is useful for flow cytometric detection of CD252 on stimulated mouse splenocytes. It has also been reported to block the costimulatory activity of ≥≥OX-40 Ligand. Please choose the appropriate format for each application.

Name PerCP-Cyanine5.5 Anti-Mouse CD252 (OX40 Ligand) (RM134L)
Cat. No. 65-5905
Alternative Names CD134L, CD134 Ligand, OX-40L, OX-40 Ligand, TNF-αSF4, Tumor necrosis factor ligand superfamily member 4, gp34
Gene ID 22164
Clone RM134L
Isotype Rat IgG2b, κ
Reactivity Mouse
Format PerCP-Cyanine5.5
Application Flow Cytometry
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