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C57Bl/6 splenocytes were stimulated for 3 days with ConA and then stained with APC Anti-Mouse CD3 (20-0031) and 0.25 ug PerCP-Cyanine5.5 Anti-Mouse CD134  (65-1341) (right panel) or 0.125 ug PerCP-Cyainie5.5 Rat IgG1 (left panel).

PerCP-Cyanine5.5 Anti-Mouse CD134 (OX40) (OX-86)

SKU 65-1341-U025
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The OX-86 monoclonal antibody reacts with mouse CD134, a 50kD type 1 integral membrane glycoprotein and a member of the TNF-α receptor superfamily. CD134 is also known as OX40 and is expressed on activated CD4 and CD8 T cells. CD134 is the receptor for CD252 (OX40 ligand) and the interaction of this receptor-ligand pair is implicated in T-dependent humoral responses as well as numerous aspects of T cell expansion, survival and memory. Additionally, CD134 seems to play a significant role in the pathogenesis of some autoimmune diseases.


Recent Citations:

Lee W, Kingstad-Bakke B, Kedl RM, Kawaoka Y, Suresh M. CCR2 Regulates Vaccine-Induced Mucosal T-Cell Memory to Influenza A Virus. bioRxiv. 2021 Mar 25:2021.03.24.436901. doi: 10.1101/2021.03.24.436901. PMID: 33791695; PMCID: PMC8010722.

» View on PubMed

Name PerCP-Cyanine5.5 Anti-Mouse CD134 (OX40) (OX-86)
Cat. No. 65-1341
Alternative Names TNFRSF4, ACT35, OX-40
Gene ID 22163
Clone OX-86
Isotype Rat IgG1, kappa
Reactivity Mouse
Format PerCP-Cyanine5.5
Application Flow Cytometry
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