PerCP Anti-Mouse Ly-6G/Ly-6C (Gr-1) (RB6-8C5)
The RB6-8C5 antibody binds to mouse Ly-6G/Ly-6C, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expressed at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.
Sugimoto Y, Endo D, Aratani Y. Mice Deficient in NOX2 Display Severe Thymic Atrophy, Lymphopenia, and Reduced Lymphopoiesis in a Zymosan-Induced Model of Systemic Inflammation. Inflammation. 2020 Sep 16. doi: 10.1007/s10753-020-01342-6. PMID: 32939668.
|Name||PerCP Anti-Mouse Ly-6G (Gr-1) (RB6-8C5)|
|Alternative Names||Gr1, Ly6G|
|Isotype||Rat IgG2b, κ|