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Human lysed whole blood was stained with 5 uL (0.5 ug) PerCP Anti-Human CD45 (67-9459) (right panel) or 0.5 ug PerCP Mouse IgG1 isotype control (left panel).

PerCP Anti-Human CD45 (2D1)

SKU 67-9459-T025
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The 2D1 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, and CD45RO.

The 2D1 antibody is widely used as a marker for human CD45 expression on peripheral blood T cells, B cells, monocytes, macrophages, and NK cells.

Name PerCP Anti-Human CD45 (2D1)
Cat. No. 67-9459
Alternative Names Leukocyte Common Antigen, LCA, Ly-5, Hle-1
Gene ID 5788
Clone 2D1
Isotype Mouse IgG1, kappa
Reactivity Human
Format PerCP
Application Flow Cytometry
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