Shopping Cart
PE/Fire™ 640 anti-mouse CD278 (ICOS)

PE/Fire™ 640 anti-mouse CD278 (ICOS)

SKU 107713
Regular price

$98.00

task_alt Added to cart.
View Cart or Continue shopping.
Description

CD278 is a 47-57 kD protein, also known as inducible costimulatory molecule (ICOS), or H4. This protein is homologous to the CD28/CTLA-4 proteins. It forms homodimers and is expressed on activated T cells and a subset of thymocytes. It is able to costimulate T cells proliferation. In addition, ICOS has been shown to be involved in humoral immune responses (B cell germinal center formation). The ICOS ligand is B7-H2. ICOS stimulation has been shown to potentiate TCR-mediated IL-4 and IL-10 production and has been proposed to play a role in Th2 cell development. It has also been shown to be involved in airway tolerance and the downregulation of pulmonary inflammation.


PRODUCT DETAILS

Clone: 15F9

Antibody Type: Monoclonal

Reactivity: Mouse

Format: PE-Fire 640

Host: Syrian Hamster

Isotype: IgG

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS



Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.

Shipping
Price calculated at checkout.