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C57Bl/6 bone marrow cells were stained with 0.25 ug PE-Cy7 Anti-Mouse Ly-6G (60-1276) (solid line) or 0.25 ug PE-Cy7 Rat IgG2a isotype control (dashed line).

PE-Cyanine7 Anti-Mouse Ly-6G (1A8)

SKU 60-1276-U025
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$62.00

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Description

TDS | SDS

The 1A8 antibody binds to mouse Ly-6G, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Ly-6G is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.

In the mouse, the 1A8 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: for identification of Ly-C, an alternative antibody, clone RB6-8C5, has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C.

Recent Publications:
Lin CC, Bradstreet TR, Schwarzkopf EA, Jarjour NN, Chou C, Archambault AS, Sim J, Zinselmeyer BH, Carrero JA, Wu GF, Taneja R, Artyomov MN, Russell JH and Edelson BT. 2016. J Exp Med. 213(2): 251-271. (Flow Cytometry)

Name PE-Cyanine7 Anti-Mouse Ly-6G (1A8)
Cat. No. 60-1276
Gene ID 546644
Clone 1A8
Isotype Rat IgG2a, κ
Reactivity Mouse
Format PE-Cyanine7
Application Flow Cytometry
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