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C57Bl/6 splenocytes were stained with 0.125 ug PE-Cy7 Anti-Mouse CD45 (60-0451) (solid line) or 0.125 ug PE-Cy7 Rat IgG2b isotype control (dashed line).

PE-Cyanine7 Anti-Mouse CD45 (30-F11)

SKU 60-0451-U025
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$49.00

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Description

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The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.

The 30-F11 antibody is widely used as a leukocyte marker for B cells, T cell subsets and NK cell subsets.

 

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Name PE-Cyanine7 Anti-Mouse CD45 (30-F11)
Cat. No. 60-0451
Alternative Names Leukocyte Common Antigen, LCA, Ly-5
Gene ID 19264
Clone 30-F11
Isotype Rat IgG2b, κ
Reactivity Mouse
Format PE-Cyanine7
Application Flow Cytometry
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