CD226 (DNAM-1) is constitutively expressed on native CD8⁺ cells and on CD4⁺ T cells, macrophages and NK cells.This antibody (10E5) was reported to bind about 40% of inactivated CD4⁺ cells and binds only to differentiated Th1 cells, but not to Th2 or Th0 cells.It is also reported to suppress antigen-specific T cell expansion and EAE (experimental allergic encephalitis) mediated by Th1 cells.

PRODUCT DETAILS

Clone: 10E5

Antibody Type: Monoclonal

Reactivity: Mouse

Format: PE-Cyanine7

Host: Rat

Isotype: IgG2b, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.