The mouse monoclonal antibody clone MEM-06 binds to the human CD41 antigen (also known as the human integrin α2b and GPIIb). CD41 is a 125 kDa single-pass type 1 transmembrane glycoprotein that is expressed by platelets, megakaryocytes, mast cells, and hematopoietic progenitors. It forms a heterodimer with CD61 (integrin β3), which interacts with several ligands including, fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is involved in the processes of coagulation and aggregation, and defects in CD41 can lead to coagulation disorders.

PRODUCT DETAILS

Clone: MEM-06

Specificity: CD41

Reactivity: Human

Format: PE-Cyanine7

Isotype: Mouse IgG1

Tested Dilution: 5 µL/Test

Application: FC

Storage: 2-8°C protected from light.Do not freeze

Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Flow cytometry: The suggested use of this reagent is 5 µL per 1 million cells in a staining volume of 100 µL. If whole blood is analyzed, then use 5 µL per 100 µL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application. The content of a vial (0.5 mL) is sufficient for 100 tests.

For research use only. Not intended for use in diagnostic procedures.

PE-Cyanine7 is a tandem dye made with PE. Caution – Tandem dyes may show changes in their emission spectra with prolonged exposure to light or fixatives.