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Human peripheral blood lymphocytes were stained with 5 uL (0.25 ug) PE-Cyanine5 Anti-Human CD45 (55-9459) (solid line) or 0.25 ug PE-Cyanine5 Mouse IgG1 isotype control (dashed line).

PE-Cyanine5 Anti-Human CD45 (2D1)

SKU 55-9459-T025
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$98.00

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Description

TDS | SDS

The 2D1 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, and CD45RO.

The 2D1 antibody is widely used as a marker for human CD45 expression on peripheral blood T cells, B cells, monocytes, macrophages, and NK cells.

Name PE-Cyanine5 Anti-Human CD45 (2D1)
Cat. No. 55-9459
Alternative Names Leukocyte Common Antigen, LCA, Ly-5, Hle-1
Gene ID 5788
Clone 2D1
Isotype Mouse IgG1, kappa
Reactivity Human
Format PE-Cyanine5
Application Flow Cytometry
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