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C57Bl/6 splenocytes were stained with 0.06 ug Anti-Mouse MHC Class II PE (50-5321) (solid line) or 0.06 ug Rat IgG2b PE isotype control (dashed line).

PE Anti-Mouse MHC Class II (I-A/I-E) (M5/114.15.2)

SKU 50-5321-U025
Regular price

$38.00

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Description

TDS | SDS

The M5/114.15.2 antibody reacts with mouse MHC Class II alloantigens I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek, as well as being cross-reactive with mouse cells of H-2p and H-2r haplotype. MHC Class II is widely expressed by mouse immune cells bearing these alloantigens, including T and B cells, monocytes, macrophages, and dendritic cells. The antibody does not react with the following alloantigens: I-Af, I-Ak, I-As, or NOD H-2g7

The M5/114.15.2 antibody may be used for analysis of mouse cells expressing MHC Class II alloantigens as described. Please note that the M5/114.15.2 clone may also be referred to as M5/114 in the literature.

 

Recent Publications:

Clark NM, Martinez LM, Murdock S, deLigio JT, Olex AL, Effi C, Dozmorov MG, Bos PD. Regulatory T Cells Support Breast Cancer Progression by Opposing IFN-γ-Dependent Functional Reprogramming of Myeloid Cells. Cell Rep. 2020 Dec 8;33(10):108482. doi: 10.1016/j.celrep.2020.108482. PMID: 33296659.

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Name PE Anti-Mouse MHC Class II (I-A/I-E) (M5/114.15.2)
Cat. No. 50-5321
Alternative Names MHC II, IA, IE, I-A/E, IA/IE
Gene ID 14961/14969
Clone M5/114.15.2
Isotype Rat IgG2b, κ
Reactivity Mouse
Format PE
Application Flow Cytometry
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