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C57Bl/6 splenocytes were stained with APC Anti-Mouse CD4 (20-0042), followed by intracellular staining with 0.25 ug PE Anti-Mouse Foxp3 (50-0191) (right panel) or 0.25 ug PE Rat IgG2b isotype control (left panel).

PE Anti-Mouse Foxp3 (MF23)

SKU 50-0191-U025
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The MF23 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is a member of the forkhead box or winged helix family of transcription factors and is expressed at constitutively high levels in Treg cells. Forced expression of Foxp3 in conventional T cells results in the upregulation of Treg associated molecules such as CD25, CTLA-4, and GITR and is sufficient to impart suppressive functional activity to these cells.

Name PE Anti-Mouse Foxp3 (MF23)
Cat. No. 50-0191
Alternative Names Forkhead box P3, Scurfin, JM2
Gene ID 20371
Clone MF23
Isotype Rat IgG2b
Reactivity Mouse
Format PE
Application Flow Cytometry
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