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C57Bl/6 splenocytes were stained with 0.25 ug PE Anti-Mouse CD40 (50-8050) (solid line) or 0.25 ug PE Rat IgG2a isotype control (dashed line).

PE Anti-Mouse CD40 (FGK45)

SKU 50-8050-U025
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The FGK45 antibody reacts with mouse CD40, a 40-50 kDa glycoprotein member of the tumor necrosis factor receptor (TNFR) family. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells, and macrophages. The interaction of CD40 and its ligand CD154, expressed on activated T cells, plays an essential role in mediating a broad range of immune and inflammatory responses including T cell dependent immunoglobulin class switching, germinal center formation, and the development of memory B cells.

The FGK45 clone is reported to be functionally useful for both in vitro and in vivo activation of CD40 expressing antigen presenting cells.

Name PE Anti-Mouse CD40 (FGK45)
Cat. No. 50-8050
Alternative Names Bp50, gp39, HIGM1, IGM, IMD3, T-BAM, TRAP, TNFRSF5, p50, FGK4.5
Gene ID 21939
Clone FGK45
Isotype Rat IgG2a
Reactivity Mouse
Format PE
Application Flow Cytometry
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