PE Anti-Mouse CD275 (B7-H2) (HK5.3)
The HK5.3 antibody reacts with mouse CD275, an approximately 40 kDa protein that is a member of the Ig superfamily. CD275 is also known as B7-H2, ICOS ligand, and B7-RP1. CD275 is a ligand for ICOS (CD278) that is expressed on activated T cells. CD275 is expressed by antigen presenting cells including B cells, macrophages, and dendritic cells. The interaction of CD275 with its receptor ICOS plays an important role in T cell costimulation.
|Name||PE Anti-Mouse CD275 (B7-H2) (HK5.3)|
|Alternative Names||B7h, B7-H2, GL50, ICOS Ligand|
|Isotype||Rat IgG2a, κ|