PE anti-mouse CD267 (TACI)
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Description
Transmembrane Activator and CAML Interactor (TACI) is a tumor necrosis factor receptor superfamily (TNFSF) member. It is a type III transmembrane protein sharing a high degree of homology with B cell maturation antigen (BCMA) among TNFSF members. It binds to the ligands BAFF (BLyS) and APRIL. CD267 appears to be particularly important for the regulation of B cell survival and maturation in the spleen. It is a major mediator of BAFF-dependent costimulatory responses in peripheral B cells. Signaling through TACI may serve to down-regulate B cell activity as well. The actual role for TACI in the mouse has still not been fully determined.
PRODUCT DETAILS
Clone: 8F10
Antibody Type: Monoclonal
Reactivity: Mouse
Format: PE
Host: Rat
Isotype: IgG2a, κ
Applications: FC - Quality tested
Regulatory Status: RUO
Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.