CD262, also known as DR5, TRAIL-R2, Apo-2, TRICK2, and KILLER, is a 55 kD protein. DR5 is member 10B of the TNF receptor superfamily (TNFRSF10B), widely expressed in normal tissues and some tumor cell lines. The DR5 receptor binds to TRAIL and interacts with the cytoplasmic proteins TRADD and RIP. TRAIL binding to DR5 activates NF- κB and induces apoptosis. DR5 is induced by wild-type p53.

PRODUCT DETAILS

Clone: W18111A

Antibody Type: Monoclonal

Reactivity: Mouse

Format: PE

Host: Rat

Isotype: IgG2a, λ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.