Hydrogen voltage-gated channel 1 (HVCN1) is a voltage gated, proton-selective channel expressed in immune cells, spermatozoa, and upper respiratory tract epithelial cells. HVCN1 mediates proton conductance to prevent membrane depolarization and cytoplasmic acidification. In phagocytes, it is required for the oxidative burst that underlies microbial killing, and in B cells, it facilitates antibody production. HVCN1 can also regulate functions in other cells including spermatozoa.

PRODUCT DETAILS

Clone: W23068A

Antibody Type: Monoclonal

Reactivity: Human

Format: HVCN1

Host: Rat

Isotype: IgG2a, κ

Applications: ICFC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.