Epidermal growth factor receptor variant III (EGFRvIII) arises from an in-frame deletion of exons 2 to 7 in the extracellular region of EGFR, resulting in a truncated receptor that is constitutively active. This mutation is cancer-specific and is present in approximately 50% of glioblastoma tumors.

PRODUCT DETAILS

Clone: DH8.3.Rec

Antibody Type: Recombinant

Reactivity: Human

Format: EGFRvIII

Host: Mouse

Isotype: IgG1, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

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