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Human peripheral blood lymphocytes were stained with 5 uL (0.125 ug) PE Anti-Human CD45 (50-0459) (solid line) or 0.125 ug PE Mouse IgG1 isotype control (dashed line).

PE Anti-Human CD45 (HI30)

SKU 50-0459-T025
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The HI30 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others.

The HI30 antibody is widely used as a marker for human CD45 expression on T cells, B cells, monocytes, macrophages, and NK cells.

Name PE Anti-Human CD45 (HI30)
Cat. No. 50-0459
Alternative Names Leukocyte Common Antigen, LCA, Ly-5
Gene ID 5788
Clone HI30
Isotype Mouse IgG1, kappa
Reactivity Human
Cross Reactivity Chimpanzee
Format PE
Application Flow Cytometry
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