The antibody MEM-268 recognizes extracellular part of CD30 (Ki-1 antigen), a 105 kDa single chain glycoprotein expressed on Hodgkin's and Reed-Sternberg cells; it is also found in Burkitt's lymphomas, virus-infected T and B lymphocytes, and on normal B and T lymphocytes after activation (T lymphocytes that produce Th2-type cytokines and on CD4+/CD8+ T lymphocytes that co-express CD45RO and the IL4 receptor).

PRODUCT DETAILS

Clone: MEM-268

Specificity: CD30

Reactivity: Human

Format: PE

Isotype: Mouse IgG2a, k

Tested Dilution: 5 µL/Test

Application: FC

Storage: 2-8°C protected from light.Do not freeze

Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Flow cytometry: The suggested use of this reagent is 5 µL per 1 million cells in a staining volume of 100 µL. If whole blood is analyzed, then use 5 µL per 100 µL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application. The content of a vial (0.5 mL) is sufficient for 100 tests.

REFERENCES

1. Wright CW, et al. 2007. J Biol Chem 282:10252-62.
2. Zeiser R, et al. 2007. Blood 109:2225-33.
3. Kusanovic JP, et al. 2007. J Matern Fetal Neonatal Med 20:867-78.
4. Bekiaris V, et al. 2007. J Immunol 179:7535-43.
5. Polte T, et al. 2006. J Allergy Clin Immunol 118:942-8.
6. Kennedy MK, et al. 2006. Immunology 118:143-52.
7. Fischer M, et al. 2006. J Clin Invest 116:2748-56.
8. Blazar BR, et al. 2004. J Immunol 173:2933-41.
9. Pavlov I, et al. 2009. Clin Vaccine Immunol 16:1327-31.

For research use only. Not intended for use in diagnostic procedures.