The mouse monoclonal antibody UIC2 recognizes an extracellular epitope on CD243 (MDR-1), an approximately 170 kDa ABC transporter expressed on hematopoietic stem cells, B, T, and NK cells, or on many multidrug resistant cancer cells. This antibody preferentially recognizes CD243 in the process of transporting substrate.

PRODUCT DETAILS

Clone: UIC2

Specificity: CD243

Reactivity: Human

Format: PE

Isotype: Mouse IgG2a, k

Tested Dilution: 5 µL/Test

Application: FC

Storage: 2-8°C protected from light.Do not freeze

Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Flow cytometry: The suggested use of this reagent is 5 µL per 1 million cells in a staining volume of 100 µL. If whole blood is analyzed, then use 5 µL per 100 µL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application. The content of a vial (0.5 mL) is sufficient for 100 tests.

REFERENCES

1. Kelley DJ, et al. 1993. Arch Otolaryngol Head Neck Surg 119:411-4.
2. Collnot EM, et al. 2010. Mol Pharm 7:642-51.
3. Goda K, et al. 2007. J Pharmacol Exp Ther 320:81-8.
4. Mechetner EB, et al. 1992. Proc Natl Acad Sci U S A 89:5824-8.

For research use only. Not intended for use in diagnostic procedures.