QA20A42 recognizes human CD238 also known as the kell blood group antigen Kpbc, KELL and ECE3. CD238 is an approximately 115 kD type II transmembrane glycoprotein that is encoded by the KEL gene. CD238 is expressed on erythrocytes, human embryonic stem cell-derived endoderm and on cells from various other tissues, including testis, heart, brain and skeletal muscle. CD238 functions as a zinc endopeptidase that cleaves endothelin-3 into an active form which can function as a vasoconstrictor. Decreased expression of CD238 is associated with the McLeod phenotype as a consequence of losing XK protein expression.

PRODUCT DETAILS

Clone: QA20A42

Antibody Type: Recombinant

Reactivity: Human

Format: PE

Host: Mouse

Isotype: IgG1, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.