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In Vivo Ready™ Anti-Mouse CD279 (PD-1) (RMP1-30)

In Vivo Ready™ Anti-Mouse CD279 (PD-1) (RMP1-30)

SKU 40-9981-U100
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The RMP1-30 antibody is specific for mouse CD279, also known as programmed death-1 (PD-1), a 55 kDa glycoprotein member of the Ig superfamily of molecules. PD-1 exists in a monomeric form that is expressed by CD4- CD8- thymocytes, where it participates in the processes of clonal selection, elimination of autoreactive lymphocytes, and development of tolerance. PD-1 expression is also inducible upon activation of mature T cells, where it has been proposed to interact with the co-stimulatory receptor CD80 to limit T cell activation. Two ligands for PD-1, known as PD-L1 (B7-H1) and PD-L2 (B7-DC) are differentially expressed on T and B cells, monocytes, macrophages, NK cells or dendritic cells.

Name In Vivo Ready™ Anti-Mouse CD279 (PD-1) (RMP1-30)
Cat. No. 40-9981
Data Sheets TDS | SDS
Alternative Names PD1, PD-1, RMP1-30, CD279
Gene ID 18566
Clone RMP1-30
Isotype Rat IgG2b, κ
Reactivity Mouse
Format In Vivo Ready™
Application FC - Validated
FA - Reported in literature, not validated in house

For Research Use Only. Not intended for use in diagnostic procedures.

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