The mouse monoclonal antibody AFP-01 reacts with human alpha-Fetoprotein (AFP), a 70 kDa oncofetal antigen. AFP is a major fetal plasma protein, but is not present in healthy adult tissues. Elevated AFP concentrations in adult plasma may be an early marker of hepatocellular carcinoma or teratoblastoma, while high concentrations in amniotic fluid may indicate severe congenital defects of a fetus.

PRODUCT DETAILS

Clone: AFP-01

Specificity: Alpha-Fetoprotein

Reactivity: Human

Format: HRP

Isotype: Mouse IgG1

Application: WB, ELISA

Storage: 2-8°C protected from light.Do not freeze

Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 0.01% thimerosal

Data Sheets: TDS | SDS

RECOMMENDED USAGE

ELISA: This antibody is being used as detection antibody in combination with capture antibody AFP-11.

REFERENCES

1. Stefanová I, et al. 1988. J Immunol Methods 111:67-73.
2. Cavin LG, et al. 2004. Cancer Res 64:7030-8.
3. Green CJ, et al. 2017. Cell Tissue Bank 18:597-604.
4. Colquhoun DR, et al. 2009. Environ Health Perspect 117:832-8.
5. Wang Z, et al. 2019. Mol Med Rep 19:4623-4630.

For research use only. Not intended for use in diagnostic procedures.