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C57Bl/6 T cells, enriched from total splenocytes, were stimulated with PMA and ionomycin for 6 hours and stained with 0.25 ug FITC Anti-Mouse CD154 (35-1541) (solid line) or 0.25 ug FITC Armenian Hamster IgG isotype control (dashed line).

FITC Anti-Mouse CD154 (MR1)

SKU 35-1541-U025
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The MR1 antibody is specific for mouse CD154, a 39 kD glycoprotein that is primarily expressed on activated T cells. CD154 (CD40 ligand, gp39) binds to CD40 expressed on antigen presenting cells and mediates important costimulatory functions between ≥ ≥ ≥ these cells. Signals generated via cognate interactions between ≥ ≥ ≥ CD154-CD40 on activated T and B cells are required for T-dependent B cell responses. The MR1 antibody is reported to block interaction of CD154 with CD40.

Name FITC Anti-Mouse CD154 (MR1)
Cat. No. 35-1541
Alternative Names CD40L, TRAP, Ly-62, TNF-αSF5
Gene ID 21947
Clone MR1
Isotype Armenian Hamster IgG
Reactivity Mouse
Format FITC
Application Flow Cytometry
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