The mouse monoclonal antibody CLB-GB11 recognizes granzyme B, a 31 kDa serine protease expressed intracellularly in activated Tc cells and NK cells.

PRODUCT DETAILS

Clone: CLB-GB11

Specificity: Granzyme B

Reactivity: Human, Non-Human Primate

Format: FITC

Isotype: Mouse IgG1

Tested Dilution: 5 µL/Test

Application: FC

Storage: 2-8°C protected from light.Do not freeze

Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Flow cytometry: The suggested use of this reagent is 5 µL per 1 million cells in a staining volume of 100 µL. If whole blood is analyzed, then use 5 µL per 100 µL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application. The content of a vial (0.5 mL) is sufficient for 100 tests.

REFERENCES

1. Martin P, et al. 2010. J Biol Chem 285:18918-27.
2. Kummer JA, et al. 1995. Clin Exp Immunol 100:164-72.
3. Kummer JA, et al. 1995. Kidney Int 47:70-7.
4. Tak PP, et al. 1999. Clin Exp Immunol 116:366-70.
5. Rissoan MC, et al. 2002. Blood 100:3295-303.
6. Sun Y, et al. 2005. J Immunol 174:4753-60.
7. Spaeny-Dekking EH, et al. 1998. J Immunol 160:3610-6.

For research use only. Not intended for use in diagnostic procedures.