The antibody MEM-75 reacts with an extracellular epitope of CD71 antigen (transferrin receptor), a 95 kDa type II homodimeric transmembrane glycoprotein expressed on activated B and T lymphocytes, macrophages and erythroid precursors; it is lost on resting blood leukocytes. The antibody MEM-75 does not block binding of transferrin to the receptor.

PRODUCT DETAILS

Clone: MEM-75

Specificity: CD71

Reactivity: Human

Format: FITC

Isotype: Mouse IgG1, k

Tested Dilution: 5 µL/Test

Application: FC

Storage: 2-8°C protected from light.Do not freeze

Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Flow cytometry: The suggested use of this reagent is 5 µL per 1 million cells in a staining volume of 100 µL. If whole blood is analyzed, then use 5 µL per 100 µL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application. The content of a vial (0.5 mL) is sufficient for 100 tests.

REFERENCES

1. Graham RM, et al. 2007. World J Gastroenterol 13:4725-36.
2. Graham RM, et al. 2008. J Hepatol 48:327-34.
3. Taketani S. 2005. Tohoku J Exp Med 205:297-318.
4. Rouault TA. 2003. PLoS Biol 1:E79.
5. Beck Z, et al. 2010. J Lipid Res 51:286-96.
6. Sutherland DR, et al. 2020. Cytometry B Clin Cytom 98:179-192.
7. Weijler L, et al. 2022. Cancers (Basel) 14.

For research use only. Not intended for use in diagnostic procedures.