CD108 is an 80 kD GPI-linked membrane-bound semaphorin, also known as the John-Milton-Hagen (JMH) blood group antigen, semaphorin 7A, H-SEMA, and SEMAL. It contains an Ig-like domain and is expressed at low levels on erythrocytes and lymphocytes. The expression of CD108 on lymphocytes is upregulated upon activation, and it plays an important role in modulating inflammation and T-cell-mediated immune responses. CD108 is a guidance protein that is involved in central and peripheral axon growth. The interaction of CD108 with its receptor PlexinC1 induces activation of monocytes.

PRODUCT DETAILS

Clone: KS-2

Antibody Type: Monoclonal

Reactivity: Human

Format: FITC

Host: Mouse

Isotype: IgG2a, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.