The antibody MEM-226 reacts with an extracellular epitope of CD105 (Endoglin), a 90 kDa type I homodimerizing membrane glycoprotein expressed on vascular endothelial cells (small and large vessels), activated monocytes and tissue macrophages, stromal cells of certain tissues including bone marrow, pre-B lymphocytes in fetal marrow and erythroid precursors in fetal and adult bone marrow; it is also present on syncytiotrophoblast on placenta throughout pregnancy.

PRODUCT DETAILS

Clone: MEM-226

Specificity: CD105

Reactivity: Human, Rat

Format: FITC

Isotype: Mouse IgG2a

Tested Dilution: 5 µL/Test

Application: FC

Storage: 2-8°C protected from light.Do not freeze

Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Flow cytometry: The suggested use of this reagent is 5 µL per 1 million cells in a staining volume of 100 µL. If whole blood is analyzed, then use 5 µL per 100 µL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application. The content of a vial (0.5 mL) is sufficient for 100 tests.

REFERENCES

1. Zhu Y, et al. 2003. Stroke 34:2483-8.
2. Li C, et al. 2003. J Cell Sci 116:2677-85.
3. Guo B, et al. 2004. Anticancer Res 24:1337-45.
4. Warrington K, et al. 2005. Anticancer Res 25:1851-64.
5. Piao M, et al. 2006. J Atheroscler Thromb 13:82-9.
6. Schmidt D, et al. 2007. Circulation 116:I64-70.
7. Asumda FZ, et al. 2011. BMC Cell Biol 12:44.
8. Liang L, et al. 2021. Stem Cell Res Ther 12:87.
9. Zhang J, et al. 2021. Front Cell Dev Biol 9:629274.
10. Chang Y, et al. 2022. J Renin Angiotensin Aldosterone Syst 2022:1283729.

For research use only. Not intended for use in diagnostic procedures.