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cFluor™ V610 Anti-Human CD4 (SK3)

cFluor™ V610 Anti-Human CD4 (SK3)

SKU R7-20074
Regular price

$100.00

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Description

The SK3 monoclonal antibody binds to human CD4, a 59-kDa type I transmembrane glycoprotein in the immunoglobulin superfamily. The CD4 molecule is expressed predominantly on thymocytes and a subpopulation of mature T-helper lymphocytes. It is also present on monocytes at low levels1,2. CD4 plays a role in cell-cell interaction by acting as a co-receptor for MHC class II in antigen recognition. CD4 also has been shown to bind glycoprotein 120 on external envelope of HIV3. The antibody was conjugated to a fluorophore and purified by affinity chromatography.

 

PRODUCT DETAILS

Clone:                  SK3

Reactivity:          Human

Format:                cFluor™ V610

Isotype:               Mouse IgG1, κ

Tested Dilution:  5 μL / test

Application:        Flow Cytometry

Storage:               2-8°C and protected from Light. Do not freeze

Formulation:       Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% BSA (Origin USA)

Data Sheets:       TDS SDS

 

RECOMMENDED USAGE

Each lot of this antibody is quality control tested using flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per 1 million cells in a staining volume of 100 µL. If whole blood is analyzed, then use 5 µL per 100 µL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application.

 

REFERENCES

  1. Evans RL, et al. 1981. Immunol. 78:544
  2. Muench M, et al. 1997. Blood 89:1364
  3. Arno A et al. 1999. J. Infect. Dis. 180:56

 

These products are for research use only. Not intended for use in diagnostic procedures. 

 

 

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