cFluor® UV610 Anti-Human CD10 (SN5c)
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Description
The mouse monoclonal antibody clone SN5c binds to human CD10, a 100 kDa neutral endopeptidase that is a member of the metalloprotease family. CD10 is also known as the common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. In normal cells, CD10 is expressed on early B and T lymphoid precursors, neutrophils, and various epithelia. CD10 is also expressed on several lymphoma cells, including Burkitt’s, acute lymphoblastic, and follicular germinal center lymphomas. CD10 functions as an endopeptidase, is involved in B cell development, and is a mediator of neutrophil inflammatory responses. CD10 is also recognized as a biomarker for hematopoietic and tissue stem cells, with recent studies suggesting its expression may have prognostic significance in leukemia and solid tumors.
PRODUCT DETAILS
Clone: SN5c
Specificity: CD10
Reactivity: Human
Format: cFluor® UV610
Isotype: Mouse IgG1, k
Tested Dilution: 5 µL/Test
Application: Flow Cytometry
Storage: 2-8°C protected from light. Do not freeze
Formulation: Phosphate-buffered saline, pH 7.2, containing 0.1% PEG 3350, 0.1% Pluronic F-68, 0.05% Tween-20, 0.09% sodium azide and 1% BSA (BSA Country of Origin USA)
RECOMMENDED USAGE
Each lot of this antibody is quality control tested using flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 μL per 1 million cells in a staining volume of 100 μL. If whole blood is analyzed, then use 5 μL per 100 μL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application.
Please briefly centrifuge the reagent vial before use.
Use appropriate personal protective equipment per the product safety data sheet when using this product.
For research use only. Not intended for use in diagnostic procedures.
cFluor® UV610 is a tandem dye. Caution – Tandem dyes may show changes in their emission spectra with prolonged exposure to light or fixatives.
Cytek® cFluor® UV610 is StarBright™ UltraViolet 605 Dye, manufactured and provided by Bio-Rad, Inc.
StarBright is a trademark of Bio-Rad Laboratories, Inc. in certain jurisdictions. StarBright Dyes are manufactured and provided by Bio-Rad under an Agreement between Bio-Rad supplied to Cytek, being subject to certain conditions.