cFluor® UV515 Anti-Human CD226 (DNAM-1) (DX11)
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Description
The mouse monoclonal antibody clone DX11 binds to human CD226, also known as DNAM-1. CD226 is a 65 kDa type 1 transmembrane glycoprotein expressed predominantly on T cells, NK cells, monocytes, platelets, and a subset of B cells, but not on erythrocytes. It is also found on a fraction of thymocytes that coexpress high-density surface CD3. CD226 is absent in normal fibroblast cell lines as well as in tumor cell lines derived from epithelial or neural sources. CD226 is a tyrosine-phosphorylated signaling molecule involved in initial adhesion during cytotoxic T lymphocyte (CTL) or natural killer (NK) cell-mediated cytotoxicity.
PRODUCT DETAILS
Clone: DX11
Specificity: CD226 (DNAM-1)
Reactivity: Human
Format: cFluor® UV515
Isotype: Mouse IgG1, k
Tested Dilution: 5 µL/Test
Application: Flow Cytometry
Storage: 2-8°C protected from light. Do not freeze
Formulation: Phosphate-buffered saline, pH 7.2, containing 0.1% PEG 3350, 0.1% Pluronic F-68, 0.05% Tween-20, 0.09% sodium azide and 1% BSA (BSA Country of Origin USA)
RECOMMENDED USAGE
Each lot of this antibody is quality control tested using flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 μL per 1 million cells in a staining volume of 100 μL. If whole blood is analyzed, then use 5 μL per 100 μL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application.
Please briefly centrifuge the reagent vial before use.
Use appropriate personal protective equipment per the product safety data sheet when using this product.
For research use only. Not intended for use in diagnostic procedures.
cFluor® UV515 is a tandem dye. Caution – Tandem dyes may show changes in their emission spectra with prolonged exposure to light or fixatives.
Cytek® cFluor® UV515 is StarBright™ UltraViolet 510 Dye, manufactured and provided by Bio-Rad, Inc.
StarBright is a trademark of Bio-Rad Laboratories, Inc. in certain jurisdictions. StarBright Dyes are manufactured and provided by Bio-Rad under an Agreement between Bio-Rad supplied to Cytek, being subject to certain conditions.