The mouse monoclonal antibody clone CF23A01R binds to human CCR10, a seven-transmembrane G protein–coupled receptor for the chemokines CCL27 (CTACK) and CCL28 (MEC). CCR10 is expressed on subsets of T cells, including skin-homing and mucosal lymphocytes, as well as regulatory T cells and plasma cells. Through its interaction with CCL27 and CCL28, CCR10 directs lymphocyte trafficking to skin and mucosal tissues, supporting immune surveillance and epithelial barrier defense. Aberrant CCR10 expression has been implicated in chronic inflammation, autoimmune disease, and tumor progression.

PRODUCT DETAILS

Clone: CF23A01R

Specificity: CCR10

Reactivity: Human

Format: cFluor^® R659

Isotype: Mouse IgG1, k

Tested Dilution: 5 µL/Test

Application: Flow Cytometry

Storage: 2-8°C protected from light. Do not freeze

Formulation: Phosphate-buffered saline, pH 7.2, containing 0.09% sodium azide and 0.2% BSA (BSA Country of Origin USA)

Data Sheets: TDS | SDS

RECOMMENDED USAGE

Each lot of this antibody is quality control tested using flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 μL per 1 million cells in a staining volume of 100 μL. If whole blood is analyzed, then use 5 μL per 100 μL. It is recommended that users titrate the antibody to obtain the optimal result for their specific application.

Please briefly centrifuge the reagent vial before use.

Use appropriate personal protective equipment per the product safety data sheet when using this product.

For research use only. Not intended for use in diagnostic procedures.