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Brilliant Violet 605™ anti-T-bet

Brilliant Violet 605™ anti-T-bet

SKU 644817
Regular price

$252.00

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Description

T-bet, also known as T-box transcription factor T-bet, is considered to be a 'master regulator' of Th1 lymphoid development controlling the production of the cytokine IFN-γ. T-bet is widely expressed in hematopoietic cells including stem cells, NK cells, B cells, and T cells. T-bet is critical for the control of microbial pathogens, and knockout animals show multiple physiologic and inflammatory features characteristic of asthma. T-bet expression is optimally observed after IL-12 stimulation and can be suppressed by addition of the Th2 cytokine IL-4 or neutralization of IL-12.


PRODUCT DETAILS

Clone: 4B10

Antibody Type: Monoclonal

Reactivity: Human, Mouse

Format: BV605

Host: Mouse

Isotype: IgG1, κ

Applications: ICFC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS



Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.

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