β2-microglobulin (β2M) is a 12 kDa, nonpolymorphic immunoglobulin-like protein. It is a non–membrane-anchored glycoprotein that associates noncovalently with the 39–44 kDa polymorphic heavy chains of MHC class I molecules to form the HLA class I antigen complex. In association with HLA class I, β2M is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. β2M is essential for maintaining MHC class I stability and for facilitating antigen binding and presentation to the CD3/TCR complex on CD8+ T cells.

PRODUCT DETAILS

Clone: A17082A

Antibody Type: Monoclonal

Reactivity: Human

Format: beta2-microglobulin

Host: Mouse

Isotype: IgG1, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.