IL-23R is a 72 kD protein that associates with IL-12RB1 to form a heterodimer. It is a ligand for IL-23 and stimulates T, NK and some myeloid cells.  It is necessary for generation of Th17 cells but is not required for maintenance of previously generated Th17 cells.  Expression of IL-23R or mutations in the IL23R gene has been associated with autoimmunity and may also be important in tumor biology.

PRODUCT DETAILS

Clone: 12B2B64

Antibody Type: Monoclonal

Reactivity: Mouse

Format: BV421

Host: Rat

Isotype: IgG2b, κ

Applications: FC - Quality tested

Regulatory Status: RUO

Data Sheets: TDS | SDS

Note to Purchaser: This product is manufactured and supplied by BioLegend, Inc. under an agreement between BioLegend, Inc. and Cytek Biosciences, Inc. Information related to this product is provided by BioLegend, Inc.