Biotin Anti-Mouse Ly-6G/Ly-6C (Gr-1) (RB6-8C5)
The RB6-8C5 antibody binds to mouse Ly-6G/Ly-6C, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expressed at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.
Brian BF 4th, Sauer ML, Greene JT, Senevirathne SE, Lindstedt AJ, Funk OL, Ruis BL, Ramirez LA, Auger JL, Swanson WL, Nunez MG, Moriarity BS, Lowell CA, Binstadt BA, Freedman TS. A dominant function of LynB kinase in preventing autoimmunity. Sci Adv. 2022 Apr 22;8(16):eabj5227. doi: 10.1126/sciadv.abj5227. Epub 2022 Apr 22. PMID: 35452291.
|Name||Biotin Anti-Mouse Ly-6G (Gr-1) (RB6-8C5)|
|Alternative Names||Gr1, Ly6G|
|Isotype||Rat IgG2b, κ|