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C57Bl/6 bone marrow cells were stained with 0.5 ug Biotin Anti-Mouse Ly-6G (30-1276)  (solid line) or 0.5 ug Biotin Rat IgG2a isotype control (dashed line) followed by Streptavidin PE.

Biotin Anti-Mouse Ly-6G (1A8)

SKU 30-1276-U025
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The 1A8 antibody binds to mouse Ly-6G, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Ly-6G is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.

In the mouse, the 1A8 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: for identification of Ly-C, an alternative antibody, clone RB6-8C5, has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C.

Name Biotin Anti-Mouse Ly-6G (1A8)
Cat. No. 30-1276
Gene ID 546644
Clone 1A8
Isotype Rat IgG2a, κκ
Reactivity Mouse
Format Biotin
Application Flow Cytometry
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