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C57Bl/6 bone marrow cells were stained with APC Anti-Mouse CD45R (B220) (20-0452) and 0.25 ug biotin Anti-Mouse LPAM-1 (30-5887) (right panel) or 0.25 ug biotin Rat IgG2a isotype control (left panel) followed by Streptavidin PE.

Biotin Anti-Mouse LPAM-1 (DATK32)

SKU 30-5887-U025
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The DATK32 antibody is specific for a combinatorial epitope of the mouse integrin αalpha 4/beta 7 (LPAM-1) heterodimer. LPAM-1 is expressed on most mature lymphocytes and sub-populations of thymocytes and bone marrow cells. It is involved in lymphocyte adhesion and migration and is a receptor for several extracellular matrix proteins including VCAM-1, fibronectin, and MAdCAM-1.

DATK32 is reported to induce LPAM-1 dependent lymphocyte aggregation and block adhesion to VCAM-1, fibronectin, and MAdCAM-1.

Name Biotin Anti-Mouse LPAM-1 (DATK32)
Cat. No. 30-5887
Clone DATK32
Isotype Rat IgG2a, κ
Reactivity Mouse
Format Biotin
Application Flow Cytometry
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